The iconography of this work is based on the marble Virgin Mary and Child, preserved in the National Gallery of Art in Washington, dating back to the 1570s and now attributed to Benedetto da Maiano, after previously being credited to Antonio Rossellino.
This bas-relief is temporally close to the original, as indicated by the polychromy and the poplar box frame with gouache gilding, typical of the 15th century. It is also worth noting how effectively the author manages to communicate feelings of humanity and tenderness through the simple but effective position of the Virgin. This brings the work closer to the artist's other works in the Museum of Palazzo Pretorio, such as the papier-mâché cast from the same model in Washington, a modest work and therefore a workshop piece, the “Nursing Madonna” and the two versions of the “Virgin Mary and Child with St. John”.