This painting combines in the bustling scene the main episodes of the Passion of Christ, distributed over various planes, with the Crucifixion occupying the central part, and rendered particularly lively and dramatic thanks to an almost visionary use of colour, with brown and pinkish-blue nuances showing echoes of Pontormo, his first master, and Giorgio Vasari, with whom Naldini collaborated on various occasions. The work comes from the artist’s later career, and is directly inspired in the drawing of some scenes by Roman paintings by Sebastiano del Piombo and Jacopo Coppi, which he certainly saw between 1577 and 1588. On the other hand the cold colour tones remind us of works by Nordic painters, which he probably saw in Rome.
In the hospital Spedale della Misericordia, from which they come, the scenes of the Passion were matched with another similar panel, alas now lost, showing the Passion of the 10000 martyrs. In boththe paintings, the passion of Christ and that of the martyrs is presented as a path of sorrows, but also as a path of hope and final victory, and they provided a source of reflection and comfort for the hospital patients.